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Sanford-Burnham has reached new heights of excellence, thanks to our outstanding talent.Our entrepreneurial spirit fuels scientific discoveries that become tomorrow's cures.
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First impressions
Three new employees—a postdoctoral researcher, an administrative assistant and a human resources manager—give their first impressions of working at Sanford-Burnham.
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Shared resources, successes
Sanford-Burnham recognized from the start that investigators would need Institute help in having access to state-of-the-art instrumentation and facilities that no individual lab could afford. Today, the Institute boasts 30 core facilities that provide resources and expertise in everything from bioinformatics to drug discovery.
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Complementary research
Meet a new professor in Sanford-Burnham’s Diabetes and Obesity Research Center in Lake Nona. A caretaker of orphan receptors, Dr. Fraydoon Rastinejad has found in Sanford-Burnham a home of diverse and complementary
scientific talents to do his research.
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Talent - Quote Read More
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Robert Abraham, Ph.D.
Adjunct Professor, NCI-Designated Cancer Center Signal Transduction Program
Dr. Abraham investigates a variety of intracellular signaling pathways related to cell-cycle control and cancer development.
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Cristian Achim, M.D., Ph.D.
Adjunct Associate Professor, Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research Degenerative Disease Research Program
Dr. Achim's research interests included experimental models of neurodegeneration, neuroprogenitor cells, neurotrophic factors, blood brain barrier pathology and neuroimaging.
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Eileen Adamson, Ph.D.
Emeritus Professor, NCI-Designated Cancer Center
Dr. Adamson’s laboratory is working on a new way to find out which genes in cancer are deregulated using a method that scans thousands of genes at a time in a novel modification of a process called "high throughput microarray analysis".
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Salvatore Albani, M.D., Ph.D.
Director, Translational Research for Infectious and Inflammatory Disease Center Professor, Infectious and Inflammatory Disease Center Inflammatory Diseases Program
Dr. Albani studies the mechanisms of autoimmune diseases, and develops new strategies to re-direct T-cell responses.
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Judith Altarejos, Ph.D.
Assistant Professor, Diabetes and Obesity Research Center Metabolic Signaling and Disease Program
Dr. Altarejos studies how peripheral signals modulate energy balance through the regulation of gene expression in the hypothalamus.
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Rajesh Ambasudhan, Ph.D.
Research Assistant Professor, Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research
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Julio Ayala, Ph.D.
Associate Director, Cardiometabolic Phenotyping Core Assistant Professor, Diabetes and Obesity Research Center Metabolic Signaling and Disease Program
Dr. Ayala’s research focuses on the role of the incretin hormone glucagon-like peptide-1 (Glp-1) and its receptor in the regulation of fuel metabolism.
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Bas Baaten, Ph.D.
Assistant Professor, Infectious and Inflammatory Disease Center Inflammatory Diseases Program
Dr. Baaten studies host-pathogen interactions at the respiratory mucosa with the goal of developing strategies to modulate immunity after infection with influenza virus.
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Timothy Baker, Ph.D.
Adjunct Professor, Infectious and Inflammatory Disease Center Infectious Diseases Program
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Anne Bang, Ph.D.
Director, Cell-based Disease Modeling and Screening Staff, Conrad Prebys Center for Chemical Genomics
Anne Bang develops induced pluripotent stem cell (iPSC) based disease models for drug screening.
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Rolf Bodmer, Ph.D.
Professor, Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research Director, Development and Aging Program
Dr. Bodmer focuses on the molecular mechanisms of organ formation and the genetic basis of heart development and performance.
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Francesca Boscolo, M.S.
Graduate Student, Sanford-Burnham Graduate School of Biomedical Sciences
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Massimo Bottini, Ph.D.
Adjunct Assistant Professor, Infectious and Inflammatory Disease Center Infectious Diseases Program
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Phil Bourne, Ph.D.
Adjunct Professor, Infectious and Inflammatory Disease Center Bioinformatics and Systems Biology Program
Dr. Bourne works at the interface between high performance computing and biology.
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Linda Bradley, Ph.D.
Professor, Infectious and Inflammatory Disease Center Inflammatory Diseases Program
Dr. Bradley is investigating parameters that control the development of immune cells and developing ways to modulate immune cell responses during infection and autoimmune diseases.
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Wenqing Cai, M.S.
Graduate Student
Wenqing Cai is focusing on natural inducers of heart differentiation in embryonic stem cells.
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Robert Cardiff, M.D., Ph.D.
Adjunct Professor, NCI-Designated Cancer Center Tumor Development Program
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Sumit Chanda, Ph.D.
Associate Professor, Infectious and Inflammatory Disease Center Inflammatory Diseases Program
Dr. Chanda's laboratory is working to elucidate the repertoire of host proteins required for host-pathogen interaction and viral propagation in influenza A and HIV.
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Huei-Sheng Vincent Chen, Ph.D.
Associate Professor, Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research Development and Aging Program
Dr. Chen investigates the factors controlling development, maturation and function of various ion channels in cardiac and neurological systems to develop pharmacological and therapeutic interventions for cardiac arrhythmia, cardiomyopathy, and neurodegenerative diseases using stem cell-based approaches.
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Su-Li Cheng, Ph.D.
Research Assistant Professor, Diabetes and Obesity Research Center Cardiovascular Pathobiology Program
Dr. Cheng studies the roles of canonical Wnt signaling in cardiovascular function in diabetes.
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Thomas "TC" Chung, Ph.D.
Director of Outreach & Project Manager, MLPCN Staff, Conrad Prebys Center for Chemical Genomics
Dr. Chung is the Project Manager at the Sanford-Burnham Medical Research Institute's screening center.
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Piotr Cieplak, Ph.D.
Research Associate Professor, Infectious and Inflammatory Disease Center Bioinformatics and Systems Biology Program
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Giuseppina Claps, M.S.
Graduate Student
Giuseppina is interested in define specific markers for normal prostate stem cells (PSCs) applying new methods.
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Sheila Collins, Ph.D.
Professor, Diabetes and Obesity Research Center Metabolic Signaling and Disease Program
Dr. Collins's laboratory is interested in the biochemical mechanisms that regulate body weight, and is currently studying the role adrenaline receptors play in the breakdown of stored fat and the development of white vs. brown adipocytes.
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Nicholas Cosford, Ph.D.
Associate Professor, NCI-Designated Cancer Center Apoptosis and Cell Death Research Program
Dr. Cosford’s laboratory uses medicinal chemistry, chemical biology, rational drug design and microfluidic approaches to develop small-molecule modulators of cell death, survival and growth signaling pathways, for use as novel therapeutic agents to treat cancer, neurodegenerative and psychiatric disorders, and orphan diseases.
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Sara A. Courtneidge, Ph.D.
Director of Academic Affairs Professor, NCI-Designated Cancer Center Director, Tumor Microenvironment Program
Dr. Courtneidge studies Src and its substrates and their roles in invadopodia/podosome formation, cancer progression and embryonic development.
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Paula Coutino, M.S.
Graduate Student
Paula’s goal is to elucidate the individual role of Brm and Brg1-containing SWI/SNF complexes during myoblast differentiation.
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Alessandra Dall'Agnese, M.S.
Graduate Student
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Marcia Dawson, Ph.D.
Professor, NCI-Designated Cancer Center Tumor Development Program
Dr. Dawson's laboratory uses rational drug design and computational methods to understand small-molecule-protein interactions, with the goal of designing, synthesizing and optimizing new pro-apoptotic small molecules and retinoic acid analogs.
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Anthony DeMaria, M.D.
Adjunct Associate Professor, Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research Development and Aging Program
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Maria Diaz-Meco, Ph.D.
Professor, NCI-Designated Cancer Center Tumor Microenvironment Program
Dr. Diaz-Meco’s research focuses on the role of the atypical protein kinase C (aPKC) pathway in cancer and inflammation.
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Yi Ding, B.S.
Graduate Student
Yi Ding is interested in understanding structure and function of membrane protein, especially bacterial membrane protein.
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Duc Dong, Ph.D.
Assistant Professor, Sanford Children’s Health Research Center Genetic Disease Program
Dr. Dong’s group is working to decipher progenitor biology to gain insight into development and disease, and to enable genetic and pharmacologic manipulation of differentiation and regeneration.
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Gregg Duester, Ph.D.
Professor, Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research Development and Aging Program
Dr. Duester studies the function of the vitamin A metabolite retinoic acid during embryonic development, as a step toward understanding the causes and potential treatments of human birth defects.
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Domenico Fasci, B.S.
Graduate Student
Domenico Fasci is interested in the study of the SUMOylation/deSUMOylation cycle.
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Darren Finlay, Ph.D.
Research Assistant Professor, NCI-Designated Cancer Center
Dr. Finlay's research is focused on apoptosis (programmed cell death) and how this process can be manipulated to kill cancer cells.
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Rati Fotedar, Ph.D.
Professor, NCI-Designated Cancer Center Tumor Development Program
Dr. Fotedar's laboratory is working to gain a better understanding of cell cycle checkpoints and how they link DNA damage and repair, cell cycle progression, cell senescence and apoptosis.
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Hudson Freeze, Ph.D.
Professor, Sanford Children’s Health Research Center Director, Genetic Disease Program
Dr. Freeze focuses on identifying the genetic causes of Congenital Disorders of Glycosylation (CDG), and how these defects translate into disease presentation and treatment.
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Michiko Fukuda, Ph.D.
Professor, NCI-Designated Cancer Center Tumor Microenvironment Program
Dr. Fukuda's laboratory is investigating the role of glycoproteins and cell surface carbohydrates in fertility, embryonic implantation and cancer metastasis.
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Minoru Fukuda, Ph.D.
Professor, NCI-Designated Cancer Center Tumor Microenvironment Program
Dr. Fukuda's research focuses on the cell-type specific carbohydrates including sialyl-Lewis X and their roles in cell adhesion, leukocyte homing, tumor metastasis, inflammation and infectious disease.
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Stephen Gardell, Ph.D.
Senior Director of Scientific Resources at Lake Nona Associate Professor, Diabetes and Obesity Research Center Cardiovascular Pathobiology Program
Dr. Gardell directs an array of translational research technology platforms that facilitate the adancement of basic scientific discoveries from Sanford-Burnham laboratories toward potential clinical utility.
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Sara Gelino, B.S.
Graduate Student
Sara Gelino is interested in the role of autophagy in the longevity pathway of dietary restriction.
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Gregory Gibson, Ph.D.
Adjunct Professor, Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research Development and Aging Program
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Lorenzo Giordani, M.S.
Graduate Student
Lorenzo is interested in mechanism by which epigenetic events are integrated at the chromatin level to determine the sub-sets of genes that are expressed upon the commitment of embryonic or adult stem cells toward specific cell lineages.
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Adam Godzik, Ph.D.
Professor, Infectious and Inflammatory Disease Center Director, Bioinformatics and Systems Biology Program
Dr. Godzik's research uses computational and database methods to understand the relationships between protein sequence, structure and function
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Vladislav Golubkov, Ph.D.
Research Assistant Professor, Infectious and Inflammatory Disease Center Tumor Microenvironment Program
The emphasis of Dr. Golubkov's research is on the metalloprotease (MMP)-dependent oncogenesis and invasion of malignant cells.
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Ryon Graf, B.S.
Graduate Student
Ryon is interested in the dual roles of Caspase 8 in cell migration and apoptosis.
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Paul Grossfield, M.D.
Adjunct Assistant Professor, Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research Development and Aging Program
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Zezong Gu, Ph.D.
Adjunct Associate Professor, Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research Degenerative Disease Research Program
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Luca Guidotti, Ph.D., D.V.M.
Adjunct Associate Professor, Infectious and Inflammatory Disease Center Inflammatory Diseases Program
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Mirco Guigli, M.S.
Graduate Student
Mirco is mainly interested in cell-image-based high content screens (HCS).
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Tod Gulick, M.D.
Assistant Professor, Diabetes and Obesity Research Center Cardiovascular Pathobiology Program
Dr. Gulick investigates alternative splicing of transcription factors and expression and functions of the encoded splicing isoforms in muscle.
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Janna Hachmann, M.S.
Graduate Student
Janna Hachmann is interested in the oncogene known as MALT1, which plays a crucial role in certain forms of lymphoma.
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Gabriel Haddad, M.D.
Adjunct Associate Professor, Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research Development and Aging Program
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Xianlin Han, Ph.D.
Professor, Diabetes and Obesity Research Center Cardiovascular Pathobiology Program
Dr. Han's laboratory focuses on identifying the biochemical mechanism(s) underlying the altered lipid metabolism, trafficking, and homeostasis under patho(physio)logical conditions including metabolic syndrome and Alzheimer’s disease by using a lipidomics approach.
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Dorit Hanein, Ph.D.
Professor, Infectious and Inflammatory Disease Center Bioinformatics and Systems Biology Program
Dr. Hanein's group employs electron microscopy, electron tomography and three-dimensional image analysis to determine the structures of macromolecular machines, ultimately in their native context and environment.
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Malene Hansen, Ph.D.
Assistant Professor, Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research Development and Aging Program
Dr. Hansen focuses on the modulation of aging and age-related diseases by evolutionarily conserved signaling pathways and newly identified longevity genes.
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Christian Hassig, Ph.D.
Director for Drug Discovery (La Jolla) Staff Scientist, Conrad Prebys Center for Chemical Genomics
Chris provides operational and scientific oversight of the activities of the Conrad Prebys Center for Chemical Genomics.
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Craig Hauser, Ph.D.
Vice President for Scientific Resources;
Cancer Center Associate Director, Shared Resources Adjunct Associate Professor, NCI-Designated Cancer Center Tumor Development Program
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Susanne Heynen-Genel, Ph.D.
Director, High Content Screening Systems Staff, Conrad Prebys Center for Chemical Genomics
Susan directs development and execution of image-based high-content assays for high-throughput screening (primary screens of large chemical and RNAi libraries) and small scale screening (secondary assays, focused libraries, assays for validation of basic research findings)
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James Hickman, Ph.D.
Adjunct Professor, Diabetes and Obesity Research Center Cardiovascular Pathobiology Program
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Ziwei Huang, Ph.D.
Adjunct Professor, Infectious and Inflammatory Disease Center Inflammatory Diseases Program
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Michael Jackson, Ph.D.
Vice President, Drug Discovery and Development Adjunct Associate Professor, Conrad Prebys Center for Chemical Genomics
Dr. Jackson is vice president of drug discovery and development at Sanford-Burnham, where he oversees the daily operations of the chemical biology and drug discovery resources within the Conrad Prebys Center for Chemical Genomics.
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Zhen Jiang, M.D., Ph.D.
Assistant Professor, Diabetes and Obesity Research Center Metabolic Signaling and Disease Program
Dr. Jiang’s research focuses on insulin signaling networks related to metabolism and selective impairment of the PI 3-kinase–Akt pathway in obesity.
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Rongsheng Jin, Ph.D.
Adjunct Assistant Professor, Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research Degenerative Disease Research Program
Dr. Jin's interest is in the role of the NMDA receptor in synaptic plasticity and memory formation, and in brain injury and disease.
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Randal Kaufman, Ph.D.
Professor, Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research Director, Degenerative Disease Research Program
Dr. Kaufman’s current research is focused on understanding the fundamental mechanisms that regulate protein folding and the cellular responses to the accumulation of unfolded proteins within the endoplasmic reticulum.
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Marcus Kaul, Ph.D.
Assistant Professor, Infectious and Inflammatory Disease Center Inflammatory Diseases Program
Dr. Kaul's work focuses on the role of chemokines, inflammatory cytokines and their receptors in inflammatory and degenerative diseases, including the promotion or prevention of HIV-associated neurodegeneration and dementia.
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Daniel Kelly, M.D.
Senior Vice President and Scientific Director, Sanford-Burnham Medical Research Institute at Lake Nona Professor & Director, Diabetes and Obesity Research Center
Dr. Kelly investigates the molecular control of mitochondrial function and fuel metabolism in developing and diseased heart and skeletal muscle.
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Sepideh Khorasanizadeh, Ph.D.
Professor, Diabetes and Obesity Research Center Metabolic Signaling and Disease Program
Dr. Khorasanizadeh's laboratory characterizes the epigenetic mechanisms that orchestrate transcription using tools of biophysics and structural biology.
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Mehrak Kiankarimi, Ph.D.
Associate Director of Portfolio Project Management Staff, Conrad Prebys Center for Chemical Genomics
Mehrak is in charge of the center-wide implementation and customization of a web-based project/portfolio management system at CPCCG.
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Renate Koenig, Ph.D.
Adjunct Associate Professor, Infectious and Inflammatory Disease Center Inflammatory Diseases Program
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Masanobu Komatsu, Ph.D.
Associate Professor, NCI-Designated Cancer Center Tumor Microenvironment Program
Dr. Komatsu studies the role of the signaling protein R-ras in angiogenesis and vascular remodeling.
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Sunyoung Lee, Ph.D.
Assistant Professor, NCI-Designated Cancer Center Tumor Microenvironment Program
Dr. Lee focuses on how vascular endothelial growth factor (VEGF) regulates specification, morphogenesis, differentiation and homeostasis of blood vessels, both in normal and pathological conditions.
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Jean-Pyo Lee,
Adjunct Assistant Professor, Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research Stem Cells and Regenerative Biology Program
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Fred Levine, M.D., Ph.D.
Professor & Director, Sanford Children’s Health Research Center Genetic Disease Program
Dr. Levine studies the process of pancreatic beta-cell regeneration, with the goal of developing new therapies for diabetes.
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Gianluigi Lichinchi, M.S.
Graduate Student
Gianluigi is interested in understanding the mechanisms involving small RNAs and RNA-protein complexes in regulating HIV-1 cycle and host-pathogen interactions.
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Robert Liddington, Ph.D.
Professor, Infectious and Inflammatory Disease Center Director, Infectious Diseases Program
Dr. Liddington’s laboratory uses x-ray crystallography to explore the structural basis of host-pathogen interactions; the structure-function correlates of viral virulence; and the role of integrins in inflammation, hemostasis and cancer metastasis
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Kenneth Liechty, M.D.
Adjunct Faculty, Diabetes and Obesity Research Center Cardiovascular Pathobiology Program
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Stuart Lipton, M.D., Ph.D.
Professor & Director, Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research Degenerative Disease Research Program
The Lipton laboratory studies molecular mechanisms of neurodegenerative diseases and stroke, including the role of excessive stimulation of ion channels and intracellular signaling pathways in nerve cells, develops new drug treatments for these conditions, and uses stem cells, molecularly engineered to become nerve cells, for cell-replacement therapy.
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Sally Litherland, Ph.D.
Adjunct Associate Professor, Diabetes and Obesity Research Center Metabolic Signaling and Disease Program
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Jingya Liu, B.S.
Graduate Student
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Jinsha Liu, M.S.
Graduate Student
Jinsha aims to investigate the role of CDH13 and explore possible mechanisms in neuronal networks.
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Jeanne Loring, Ph.D.
Adjunct Professor, Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research Stem Cells and Regenerative Biology Program
Dr. Loring's current research focuses on the molecular basis of pluripotence and differentiation of human embryonic stem (ES) cells.
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Martin Lotz, M.D.
Adjunct Professor, Infectious and Inflammatory Disease Center Inflammatory Diseases Program
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Siobhan Malany, Ph.D.
Chemical Biology Team Leader Staff Scientist, Conrad Prebys Center for Chemical Genomics
Siobhan provides scientific consultation and execution of cell-based, organism-based, biochemical, phenotypic and stem-cell assays for HTS and drug discovery.
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Francesca Marassi, Ph.D.
Associate Professor, NCI-Designated Cancer Center Apoptosis and Cell Death Research Program
Dr. Marassi's laboratory uses solution-state and solid-state NMR spectroscopy to determine the three-dimensional structure of integral membrane proteins, which are potential therapeutic targets in cancer, heart disease and infectious disease.
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Robert Margolis, Ph.D.
Professor, NCI-Designated Cancer Center Tumor Development Program
Dr. Margolis' research focuses on the relationships between mitosis, the cell cycle, and the cellular cytoskeleton, and the regulatory mechanisms that control them.
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Jamey Marth, Ph.D.
John Carbon Chair of Biochemistry and Molecular Biology, UCSB
Duncan and Suzanne Mellichamp Chair of Systems Biology, UCSB Professor, NCI-Designated Cancer Center Tumor Microenvironment Program
The Marth laboratory incorporates biology, engineering, and nanotechnologies to expand biomedical research capabilities in order to identify the origins of disease and to design more effective means of disease diagnosis, prevention, treatment, and ultimately cure.
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Shu-Ichi Matsuzawa, Ph.D.
Research Assistant Professor, NCI-Designated Cancer Center
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Jochen Maurer, Ph.D.
Postdoctoral Fellow
Dr. Maurer studies cancer stem cells in breast cancer.
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Philip McQuary, M.S.
Graduate Student
Philip is exploring the role of the translation initiation factor eIF4E2 in protein synthesis under stressful environmental conditions.
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Angel Mei, B.S.
Graduate Student
Angel is interested in drug development through fragment based design using NMR.
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Mark Mercola, Ph.D.
Professor, Sanford Children’s Health Research Center Director, Muscle Development and Regeneration Program
Dr. Mercola's research is directed at discovering molecules that promote differentiation of cardiomyocyte progenitors that will ultimately be useful for regeneration of muscle cells that are lost in heart disease.
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José Luis Millán, Ph.D.
Professor, Sanford Children’s Health Research Center Genetic Disease Program
Dr. Millán studies the mechanisms that control normal skeletal mineralization and the pathophysiology of diverse calcification disorders, including vascular calcification.
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Jorge Moscat, Ph.D.
Professor, NCI-Designated Cancer Center Tumor Microenvironment Program
Dr. Moscat studies the signaling mechanisms controlling cell growth and proliferation.
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William Muller, Ph.D.
Adjunct Professor, NCI-Designated Cancer Center Tumor Development Program
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Christa Muller-Sieburg, Dr. rer. nat.
Professor, Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research Stem Cells and Regenerative Biology Program
Dr. Muller-Sieburg's research focuses on understanding the cellular and molecular mechanisms that regulate hematopoietic stem cells.
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Tomas Mustelin, M.D., Ph.D.
Adjunct Professor, Infectious and Inflammatory Disease Center Inflammatory Diseases Program
Dr. Mustelin investigates a family of genes called protein tyrosine phosphatase (PTPases), many of which act as tumor suppressors in numerous types of human cancer.
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Sean Oldham, Ph.D.
Research Assistant Professor, Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research
Dr. Oldham aims to understand the genetic interplay of metabolism, growth, and aging by focusing on the nutrient sensing Insulin-TOR pathway as it relates to obesity, aging, and cancer.
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Timothy Osborne, Ph.D.
Professor, Diabetes and Obesity Research Center Director, Metabolic Signaling and Disease Program
Dr. Osborne’s research examines how the body senses differences in the molecular composition of the diet to alter absorption and cellular metabolism, with a special emphasis on processes related to diabetes, obesity and atherosclerosis.
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Robert Oshima, Ph.D.
Professor, NCI-Designated Cancer Center Tumor Development Program
The Oshima laboratory investigates stem cells in breast cancer, colon cancer and human placenta development.
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Andrei Osterman, Ph.D.
Professor, Infectious and Inflammatory Disease Center Bioinformatics and Systems Biology Program
Dr. Osterman’s research team uses a systems-biology approach to reconstruct and explore metabolic and transcriptional regulatory networks, and to predict and experimentally confirm new components of those networks.
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Goon Park, M.S.
Graduate Student
Goon Ho is studying about molecular mechanism of parkinson disease.
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Elena Pasquale, Ph.D.
Professor, NCI-Designated Cancer Center Signal Transduction Program
Dr. Pasquale's research investigates the signaling pathways of Eph receptor tyrosine kinases and their ligands in order to understand their role in normal physiology and in pathological conditions such as cancer and neurological disorders.
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Giovanni Paternostro, M.D., Ph.D.
Adjunct Assistant Professor, NCI-Designated Cancer Center Apoptosis and Cell Death Research Program
Dr. Paternostro's laboratory is employing a multidisciplinary, systems-biology approach to identify optimal combinatorial drug therapies for cancer, and to understand the cardiac and metabolic alterations caused by aging and hypoxia.
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Maurizio Pellecchia, Ph.D.
Professor, Infectious and Inflammatory Disease Center Infectious Diseases Program
Dr. Pellecchia is working to characterize the three dimensional structures and intermolecular interactions of protein targets involved in cell-signaling, cancer cell transformation and virulence factors, and on combining medicinal chemistry with structure- and fragment-based drug design, to aid in the development of novel therapeutic compounds.
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Ranjan Perera, Ph.D.
Scientific Director, Analytical Genomics and Bioinformatics Associate Professor, Diabetes and Obesity Research Center Metabolic Signaling and Disease Program
Dr. Perera investigates the molecular mechanisms by which non-coding RNA might affect melanoma development in humans and identifying the link between obesity and cancer.
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Manuel Perucho, Ph.D.
Adjunct Professor, NCI-Designated Cancer Center Tumor Development Program
Dr. Perucho is studying the role of genetic and epigenetic alterations in the development of hereditary and nonhereditary gastrointestinal cancers.
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Scott Peterson, Ph.D.
Professor, Infectious and Inflammatory Disease Center Bioinformatics and Systems Biology Program
Dr. Peterson studies microbes that live on our skin, in our mouths, and in our guts that help keep us healthy.
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Matthew Petroski, Ph.D.
Assistant Professor, NCI-Designated Cancer Center Signal Transduction Program
Dr. Petroski studies how proteins are modified with ubiquitin and ubiquitin-like proteins.
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Anthony Pinkerton, Ph.D.
Director of Chemistry Staff, Conrad Prebys Center for Chemical Genomics
Dr. Pinkerton directs the hit to lead and lead optimization efforts of Conrad Prebys Center for Chemical Genomics.
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Garth Powis, D.Phil.
Jeanne and Gary Herberger Leadership Chair in Cancer Research Professor & Director, NCI-Designated Cancer Center
Dr. Powis studies the mechanisms that enable cancer cells to survive stress.
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Richard Pratley, M.D.
Professor, Diabetes and Obesity Research Center Metabolic Signaling and Disease Program
The Pratley lab focuses on the role of adipose tissue and adipocyte secreted products in the pathogenesis of type 2 diabetes and its complications.
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Jeffrey Price, M.D., Ph.D.
Associate Professor, NCI-Designated Cancer Center Signal Transduction Program
Dr. Price's laboratory is focused on the development of fully automated, quantitative microscopy, or scanning cytometry, for biomedical applications.Â
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Pier Lorenzo Puri, M.D., Ph.D.
Associate Professor, Sanford Children’s Health Research Center Muscle Development and Regeneration Program
Dr. Puri investigates the molecular mechanisms underlying the reprogramming of the genome during cell lineage commitment and terminal differentiation.
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Tariq Rana, Ph.D.
Professor, Sanford Children’s Health Research Center Director, RNA Biology Program
The Rana laboratory is studying the architecture and function of RNA Regulatory assemblies involved in stem cell creation and their fate decisions, RNA interference (RNAi), innate immunity, host-pathogen interactions, HIV-1 replication, and RNA therapeutics.
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Barbara Ranscht, Ph.D.
Professor, NCI-Designated Cancer Center Tumor Microenvironment Program
The research focus of the Ranscht laboratory is to understand the molecular basis of cell-cell communication in the nervous- and cardiovascular system, with special focus on the role of cell surface glycoproteins in the establishment and function of neuronal circuitries, and on cell surface receptors that mediate functions of the metabolic hormone adiponectin.
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Fraydoon Rastinejad, Ph.D.
Professor, Diabetes and Obesity Research Center Metabolic Signaling and Disease Program
Dr. Rastinejad’s laboratory is interested in the nuclear hormone receptors that regulate metabolic pathways, and studies these transcription factors using crystallographic, biochemical and small molecule approaches.
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Eugene Redmond,
Adjunct Professor, Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research Stem Cells and Regenerative Biology Program
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John C. Reed, M.D., Ph.D.
Adjunct Professor, NCI-Designated Cancer Center Apoptosis and Cell Death Research Program
Dr. Reed’s laboratory studies the fundamental mechanisms of cell life-span regulation, how the defective regulation of programmed cell death mechanisms result in disease, and the role of NLR-family proteins in innate immunity, inflammation and infectious disease.
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Andreas Reiff , M.D.
Adjunct Professor, Infectious and Inflammatory Disease Center Inflammatory Diseases Program
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Tannishtha Reya, Ph.D.
Adjunct Professor, NCI-Designated Cancer Center Tumor Development Program
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Wanda Reynolds, Ph.D.
Associate Investigator, Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research
Dr. Reynolds studies the aberrant expression of MPO, an oxidant generating enzyme, in diseases of aging, and investigates how it contributes to neurodegenerative disease, atherosclerosis, and cancer.
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Adam D. Richardson, Ph.D.
Research Assistant Professor, NCI-Designated Cancer Center Signal Transduction Program
Dr. Richardson studies the role of tumor cell metabolism in tumor progression and metastasis.
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Robert Rickert, Ph.D.
Associate Dean, Graduate Program Professor, Infectious and Inflammatory Disease Center Director, Inflammatory Diseases Program
Dr. Rickert's laboratory is working to better understand the molecular determinants of B lymphocyte differentiation in normal and disease states.
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Stefan Riedl, Ph.D.
Associate Professor, NCI-Designated Cancer Center Apoptosis and Cell Death Research Program
Dr. Riedl research is centered on understanding the structure and mechanisms of signaling proteins as well as their complexes and signaling platforms in light of pathway regulation and disease.
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Dmitry Rodionov, Ph.D.
Research Assistant Professor, Infectious and Inflammatory Disease Center Bioinformatics and Systems Biology Program
Dr. Rodionov studies functional and comparative genomics of microbial genomes.
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Ze'ev Ronai, Ph.D.
Scientific Director, Sanford-Burnham Medical Research Institute at La Jolla Professor & Associate Director, NCI-Designated Cancer Center Director, Signal Transduction Program
Dr. Ronai's group is working to understand the regulation and function of mammalian stress-response signaling pathways.
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Gregory Roth, Ph.D.
Director, Medicinal Chemistry Associate Professor, Diabetes and Obesity Research Center Cardiovascular Pathobiology Program
Dr. Roth's research program focuses on the synthesis and development of biologically active natural products and related analogs relevant to biomedical research.
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Pilar Ruiz-Lozano, Ph.D.
Adjunct Assistant Professor, Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research Development and Aging Program
Dr. Ruiz-Lozano's research focuses on the developmental pathways that induce the formation of the coronary vasculature, and how coronary precursors influence cardiac morphogenesis and function.
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Erkki Ruoslahti, M.D., Ph.D.
Distinguished Professor, NCI-Designated Cancer Center Tumor Microenvironment Program
Dr. Ruoslahti’s laboratory is investigating potential therapeutic targets in tumor vasculature using vascular and lymphatic homing peptides, and they also study the mechanisms by which metastatic tumor cells overcome adhesion-dependent survival signals.
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Alessandra Sacco, Ph.D.
Assistant Professor, Sanford Children’s Health Research Center Muscle Development and Regeneration Program
Dr. Sacco's laboratory is investigating the self-renewal mechanism of skeletal muscle stem cells and determining how this process applies to muscle degenerative diseases.
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Guy Salvesen, Ph.D.
Dean, Graduate School of Biomedical Sciences Professor, NCI-Designated Cancer Center Director, Apoptosis and Cell Death Research Program
Dr. Salvesen's research focuses on the central role of enzyme pathways in the intrinsic life span and death of cells.
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Takumi Satoh, Ph.D.
Adjunct Professor, Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research Degenerative Disease Research Program
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Arnold Satterthwait, Ph.D.
Associate Professor, Infectious and Inflammatory Disease Center Infectious Diseases Program
Dr. Satterthwait's laboratory is using synthetic peptidomimetics to mimic critical three-dimensional regions of proteins, assess new theories of disease at the molecular level and to develop diagnostic tests, cancer drugs, and vaccines.
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Judith Scheliga, M.S.
Graduate Student
Judith Scheliga focuses on elucidating the biochemical pathways controlled by eIF3e and on linking its loss during breast carcinogenesis to its potential role in stress-specific translation and apoptosis.
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Peter Seeberger, Ph.D.
Adjunct Professor, NCI-Designated Cancer Center Tumor Microenvironment Program
Dr. Seeberger research is focused on elucidating the role of complex oligosaccharides involved in a host of biological processes of medical relevance by employing molecular tools created by synthetic chemistry.
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Eduard Sergienko, Ph.D.
Director, Assay Development Staff, Conrad Prebys Center for Chemical Genomics
Eduard provides scientific oversight of the HTS assay development and molecular pharmacology.
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Jeffrey Smith, Ph.D.
Professor, NCI-Designated Cancer Center Tumor Microenvironment Program
Dr. Smith’s laboratory is interested in developing new methods for proteomics, with implications for cancer and infectious diseases.
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Layton Smith, Ph.D.
Director, Drug Discovery Florida Assistant Professor, Diabetes and Obesity Research Center Cardiovascular Pathobiology Program
Dr. Smith studies the role of apelin and its receptor in cardiovascular function.
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Steven Smith, M.D.
Director, Translational Research Institute & Co-Director, Translational Research for DOC Professor, Diabetes and Obesity Research Center Metabolic Signaling and Disease Program
Dr. Smith’s research focuses on the control of metabolic substrate switching between fat and carbohydrate, with a particular emphasis on the regulation of fatty acid oxidation in skeletal muscle and the adipose tissue dysfunction that occurs in obesity.
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David Smotrich, M.D.
Clinical Associate
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Evan Snyder, M.D., Ph.D.
Professor, Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research Director, Stem Cells and Regenerative Biology Program
Dr. Snyder's laboratory is using a multidisciplinary approach to explore the basic biology of stem cells, their role throughout the lifetime of an individual, and their therapeutic potential in homeostasis and injury recovery.
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Stephen Soonthornvacharin, B.S.
Graduate Student
Stephen is interested in employing a systems-based approach, which will integrate a series of functional genomics analyses to identify novel molecular factors in RIG-I-dependent type-I interferon signaling.
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Joachim Spiess, M.D., Ph.D.
Adjunct Professor, Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research Degenerative Disease Research Program
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Charles Spruck, Ph.D.
Assistant Professor, NCI-Designated Cancer Center Signal Transduction Program
Dr. Spruck studies the roles of ubiquitin-dependent proteolysis and cell cycle proteins in the regulation of cell division and tumor development.
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Geetha Srikrishna, Ph.D.
Research Assistant Professor, NCI-Designated Cancer Center
Dr. Srikrishna is studying the role of damage associated molecular patterns (DAMP) in mediating inflammation and cancers.
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William Stallcup, Ph.D.
Professor, NCI-Designated Cancer Center Tumor Microenvironment Program
The Stallcup laboratory studies the cell surface protein NG2 and its role in the proliferation and motility of both normal and cancer cells.
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Alex Strongin, Ph.D.
Professor, Infectious and Inflammatory Disease Center Infectious Diseases Program
Dr. Strongin's research focuses on the fundamental mechanisms by which proteolysis and proteinases enable cell migration, cell proliferation and tumor cell metastasis, and by which the host, viral and bacterial proteinases affect host-pathogen interactions.
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Srikrishna Subramanian, Ph.D.
Adjunct Professor, Infectious and Inflammatory Disease Center Bioinformatics and Systems Biology Program
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Lutz Tautz, Ph.D.
Research Assistant Professor, Infectious and Inflammatory Disease Center
Dr. Tautz is a chemical biologist—integrating the fields of organic and medicinal chemistry, biochemistry, and molecular and cell biology.
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Tambet Teesalu, Ph.D.
Adjunct Assistant Professor, NCI-Designated Cancer Center Tumor Microenvironment Program
Dr. Teesalu uses phage display screens to identify homing peptides that bind to specific targets in the vasculature.
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Alexey Terskikh, Ph.D.
Associate Professor, Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research Development and Aging Program
Dr. Terskikh is interested in elucidating the mechanisms underlying self-renewing and differentiation decisions in normal and cancer stem cells.
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Victoria Thaney, B.S.
Graduate Student
Victoria’s research is focused on pathological processes associated with human immunodeficiency virus-1(HIV-1) infection, in particular HIV-1 associated dementia (HAD).
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Matthew Tierney, M.A.
Graduate Student
Matthew is interested in investigating the microenvironmental cues and cell-autonomous features that influence the regenerative potential of these different populations.
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Dwight Towler, M.D., Ph.D.
Professor, Diabetes and Obesity Research Center Director, Cardiovascular Pathobiology Program
Dr. Towler's research focuses on fundamental and early translational aspects of cardiovascular biology, physiology, and disease.
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Panagiotis Antonios Tsonis, Ph.D.
Adjunct Professor, Sanford Children’s Health Research Center Genetic Disease Program
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Shichun Tu, Ph.D.
Research Assistant Professor, Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research
Dr. Tu studies neurological disorders focusing on the potential therapeutic benefits of the synaptic protein takusan, which he identified, in the treatment of Alzheimer’s disease (AD) and on the role of the transcription factor MEF2C in the pathogenesis of Autism Spectrum Disorders (ASD).
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Björn Tyrberg, Ph.D.
Adjunct Assistant Professor, Diabetes and Obesity Research Center Metabolic Signaling and Disease Program
Dr. Tyrberg studies adult pancreatic beta-cell mass homeostasis and regulation of insulin secretion.
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Shabnam Vahidpour, M.S.
Graduate Student
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Steve Vasile, Ph.D.
Director, High Throughput Screening Staff, Conrad Prebys Center for Chemical Genomics
Steve establishes screening technologies at the institute.
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Rick Vega, Ph.D.
Research Assistant Professor, Diabetes and Obesity Research Center
Dr. Vega studies the impact of obesity and diabetes on skeletal muscle and cardiac metabolism.
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Niels Volkmann, Ph.D.
Associate Professor, Infectious and Inflammatory Disease Center Bioinformatics and Systems Biology Program
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Kristiina Vuori, M.D., Ph.D.
President Interim Chief Executive Officer & Pauline and Stanley Foster Presidential Chair
Professor, NCI-Designated Cancer Center Tumor Microenvironment Program
Dr. Vuori's laboratory is working to identify the molecular mechanisms of adhesion-dependent survival and motility in normal cells, and how tumor cells circumvent these mechanisms to enable metastasis.
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Xin Wang, B.S.
Postdoctoral Associate
Xin Wang is interested in the trafficking process of several important Alzheimer's disease (AD) related proteins, such as γ-secretase components, BACE1, APP and Neurotrophin receptors.
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Carl Ware, Ph.D.
Director, Laboratory of Molecular Immunology Professor & Director, Infectious and Inflammatory Disease Center Inflammatory Diseases Program
Dr. Ware's research is directed at defining the intercellular communicationpathways controlling immune responses, particularly to viral pathogens.
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Robert Wechsler-Reya, Ph.D.
Professor, NCI-Designated Cancer Center Director, Tumor Development Program
Dr. Wechsler-Reya’s group studies the signals that control cell growth and differentiation in the nervous system, and the manner in which these signals are dysregulated in brain tumors.
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Dieter Wolf, M.D.
Director, NCI-designated Cancer Center Proteomics Facility Professor, NCI-Designated Cancer Center Signal Transduction Program
Dr. Wolf's research focuses on the postranscriptional regulation of tumor-suppressor protein abundance and function, both at the level of protein translation and during degradation by the ubiquitin-proteasome system.
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Philip Wood, D.V.M., Ph.D.
Professor, Diabetes and Obesity Research Center Metabolic Signaling and Disease Program
Dr. Wood applies a genetic approach to investigate the role of abnormal fatty acid metabolism in rare inherited diseases and obesity-related disorders.
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John Wooley, M.D.
Adjunct Associate Professor, Infectious and Inflammatory Disease Center Bioinformatics and Systems Biology Program
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Dongxian Zhang, Ph.D.
Associate Professor, Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research Degenerative Disease Research Program
Dr. Zhang is investigating the molecular events underlying the pathogenesis of motor neuron diseases.
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Xiao-Kun Zhang, Ph.D.
Professor, NCI-Designated Cancer Center Tumor Development Program
Dr. Zhang studies the chemopreventive and therapeutic effects of vitamin A and its synthetic analogs in various cancers and diseases.
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Zhuohua Zhang, Ph.D.
Adjunct Associate Professor, NCI-Designated Cancer Center Signal Transduction Program
Dr. Zhang's research focuses on the molecular genetic mechanisms of neurodegeneration in Alzheimer’s and Parkinson’s diseases.
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Danhua Zhang, M.S.
Graduate Student
Danhua studies the development of liver and pancreas, endeavoring on defining key factors in this process.
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Runquan Zhang, Ph.D.
Postdoctoral Fellow, Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research
Runquan is interested in exploring the interactions between chemokines and chemokine receptors during various critical pathological conditions.
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Yifei Zhang, B.S.
Graduate Student
Yifei is researching molecular mechanisms of Alzheimer Disease (AD).
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Jing Crystal Zhao, Ph.D.
Assistant Professor, Sanford Children’s Health Research Center RNA Biology Program
Dr. Zhao is interested in understanding the epigenetic regulation of gene expression by large noncoding RNAs in cancer and stem cells.
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Rui Zhou, Ph.D.
Assistant Professor, Sanford Children’s Health Research Center RNA Biology Program
Dr. Zhou studies the molecular mechanism governing RNA interference (RNAi) and the role of RNAi in anti-viral immunity.
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Ying Zhou, M.S.
Graduate Student
Ying is interested in siRNA delivery in cancer therapy.
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Sanford-Burnham Medical Research Institute was founded by scientists and is led by scientists. Our interim chief executive officer and president, Kristiina Vuori, M.D., Ph.D., runs a busy laboratory that is actively seeking to understand the underlying causes of cancer and other diseases and develop new medicines. Our world-class team of administrative leaders are likewise working scientists.
Sanford-Burnham also has a Institute Advisory Board made up of leading researchers who help advance our scientific efforts. The Sanford-Burnham Board of Trustees, composed of community leaders with a passion for our work, provides strategic guidance so that our efforts remain on track and sustainable.
Board of Trustees
Founders
Dr. William H. and Lillian Fishman
Honorary Trustees
Roberta and Malin Burnham
Former Chairman, The Burnham Companies
Joe Lewis
Founder, Tavistock Group
Conrad T. Prebys
Owner, Profress Construction & Management Company
T. Denny Sanford
Chairman and CEO, United National Corp.
Trustees and Officers
M. Wainwright Fishburn, Jr.
Chairman, Sanford-Burnham Medical Research Institute
Partner, Cooley LLP
Duane J. Roth
Vice Chairman, Sanford-Burnham Medical Research Institute
CEO, CONNECT
President and
Interim Chief Executive Officer Professor, NCI-Designated Cancer Center Pauline
and Stanley Foster Presidential Chair, Sanford-Burnham Medical Research Institute
Executive Vice President Chief Administrative Officer Chief Financial Officer Treasurer, Sanford-Burnham Medical Research Institute
Margaret M. Dunbar, J.D.
Secretary, Sanford-Burnham Medical Research Institute
Lorenzo M. Berho
Founder, Chairman & President, VESTA
James C. Blair, Ph.D.
Partner, Domain Associates
Shehan Dissanayake, Ph.D
CEO, Tavistock Life Sciences
Daniel J. Epstein
President, The ConAm Group
Pauline Foster
President, Foster Investment Corporation
Patrick J. Geraghty
CEO, Florida Blue
Alan A. Gleicher
Independent Investment Management Professional
Jeanne Herberger, Ph.D.
Chairman of the Board, Hidden Meadow Ranch
Brent Jacobs
Executive Director, Cushman & Wakefield
James E. Jardon II
CEO, Jardon and Howard Technologies, Inc., and Medical Curriculum Technologies
Senior Vice President and Scientific Director, Sanford-Burnham Medical Research Institute at Lake Nona
J. Bernard Machen, D.D.D., Ph.D.
President, University of Florida
Henry L. Nordhoff
Director, MannKind Corp.
Douglas Obenshain
Member, Lockton Companies
Peter Preuss
President, Preuss Family Foundation
Andrew J. Viterbi, Ph.D.
President, Viterbi Group
Allen R. Weiss
CEO, Weiss Advisors LLC
Gayle E. Wilson
Former First Lady of California
Ex-Officio
Todd R. Golub, M.D.
Science Advisory Board Chairman
Institute Scientific Advisory Board
Bruce Beutler, M.D.
Director, Center for the Genetics of Host Defenses
UT Southwestern Medical Center
Dallas, TX
Nikola Pavletich, Ph.D.
Chair, Structural Biology Program
Memorial Sloan-Kettering Cancer Center
New York, NY
Andrea Califano, Ph.D.
Professor of Systems Biology, Columbia University
Founding Director and Chair, Columbia Initiative in Systems Biology
New York, NY
Todd Golub, M.D. (Chair)
Director, Cancer Program
Broad Institute of Harvard and MIT
Cambridge, MA
Christopher B. Newgard, Ph.D.
W. David and Sarah W. Stedman Distinguished Professor
Duke University Medical Center
Durham, NC
Victor Nizet, M.D.
Director, Division of Pharmacology & Drug Discovery
University of California, San Diego School of Medicine
La Jolla, CA
Steven M. Paul, M.D.
Department of Neurology and Neuroscience
Weill Cornell Medical College of Cornell University
New York, NY
President and
Interim Chief Executive Officer Professor, NCI-Designated Cancer Center Pauline
and Stanley Foster Presidential Chair Sanford-Burnham Medical Research Institute La Jolla, CA
Eric J. Topol, M.D.
Director, Scripps Translational Science Institute (STSI)
Chief Academic Officer, Scripps Health
La Jolla, CA
Jean Y.J. Wang, Ph.D.
Moores-UCSD Cancer Center
University of California, San Diego
La Jolla, CA
Paul A. Wender, Ph.D.
Bergstrom Professor, Department of Chemistry
Stanford University
Palo Alto, CA
Cancer Center Scientific Advisory Board
External advice regarding the scientific programs of the Cancer Center is provided by the CCSAB. CCSAB members are recognized leaders in areas of research relevant to the Center, have broad interest and knowledge in cancer research, and bring forth significant administrative and leadership expertise. CCSAB first met in 2004 after our last renewal, and has been a valuable advisory group to Dr. Vuori and the Center leadership during the last funding period.
CCSAB is chaired by Dr. Hal Moses, an internationally renowned cancer cell biologist, who is the Director Emeritus of the Vanderbilt-Ingram Cancer Center. Additional members include Drs. William Dalton, Tony Hunter, Jean Wang, and Homer Pearce.
CCSAB meets annually to review the Center, its programs, newly recruited faculty and proposed future goals, including the Five Year Scientific Plan. The CCSAB submits a written report to the Director, who shares the report with members of PPG and implements the CCSAB recommendations, as applicable.
The CCSAB guidance led to the establishment of the current four programs, and helped to shape the strategic emphasis areas within each program. The Center Director also consults with CCSAB members regarding leadership appointments within the Center, and the CCSAB members have endorsed the appointments of the new Associate Directors and Program Leaders during the past funding period.
Harold L. Moses, M.D.
Vanderbilt-Ingram Comprehensive Cancer Center – Chair
Dr. Moses is the Director Emeritus of the Vanderbilt-Ingram Cancer Center, Hortense B. Ingram Professor of Molecular Oncology, professor of Cancer Biology, Medicine and Pathology, and the founding and current director of the Frances Williams Preston Laboratories. Moses graduated from Berea College in 1958 and then obtained an M.D. degree from Vanderbilt University School of Medicine in 1962.
He is the recipient of multiple prestigious scientific awards and is well known for his work on thr transforming growth factor-beta family of growth regulatory peptides.
He is currently President of the American Association of Cancer Institutes, a member of C-Change (formerly the National Dialogue on Cancer), and a member of the Institute of Medicine of the National Academies. He Chairs the National Cancer Policy Forum of the Institute of Medicine.
Tony Hunter, Ph.D.
The Salk Institute
Tony Hunter, a professor in the Molecular and Cell Biology Laboratory and director of the Salk Institute Cancer Center, studies how cells regulate their growth and division, and how mutations in genes that regulate growth lead to cancer. His lab has made significant contributions in the area of signal transduction, how signals that stimulate or rein in growth are routed within a cell. This knowledge already has resulted in a new approach to cancer treatment.
William S. Dalton, M.D., Ph.D.
H. Lee Moffitt Cancer Center & Research Institute
Dr. Dalton was the Founding Director of the Bone Marrow Transplant Program at the University of Arizona. He is now the Chief executive Officer and Center Director of the H. Lee Moffit Cancer Center & Reserch Institute. Dr Dalton received his Ph.D. from Indianan University in Toxicology & Medical Life Sciences.
Dr. Dalton has been involved in cancer research for two decades . His research interests include biochemical mechanisms of drug resistance and new drug discovery. He is also an expert in the biology and treatment of multiple myeloma.
Homer Pearce, Ph.D.
Former Vice President at Eli Lilly Oncology Research Laboratories
Homer Pearce graduated from Texas A&M University in 1974 with a bachelor’s degree in chemistry. He earned his doctorate in organic chemistry from Harvard University in 1979, the year he joined Lilly Research Laboratories as a medicinal chemist. Dr. Pearce held several positions of increasing responsibility at Lilly, all of which were focused on the discovery and development of new drugs to treat cancer.
Since retiring from Lilly in 2006, Dr. Pearce now serves in several consulting and advisory roles in the academic, government, and biopharmaceutical communities. His personal research interests included the use of natural products as models to identify new leads for cancer drug discovery and to probe mechanisms of drug resistance. Dr. Pearce is a member of the American Association for Cancer Research, the American Chemical Society, the American Association for the Advance of Science, and C-Change.
Jean Y. J. Wang, Ph.D.
Moores UCSD Cancer Center
Dr. Wang received her Ph.D. in Biochemistry from U.C. Berkeley and was a Jane Coffin Child postdoctoral fellow at MIT. Honors include the Searle Scholar Award, a MERIT Award from the National Cancer Institute (NCI), and the Herbert Stern Endowed Chair. Dr. Wang is Associate Director of Basic Research for the UCSD Cancer Center and an editor for the journal Molecular and Cellular Biology. She has been elected to the Board of Directors of the American Association for Cancer Research and has served on the NCI Board of Scientific Counselors.
Marsha Addis
Consultant for Cancer Center Administration
External advice regarding Cancer Center Administration is provided by Marsha Addis, who consults for the Center on annual basis. Ms. Addis is former Cancer Center Associate Director for Administration and COO for Research, City of Hope National Medical Center and Beckman Research Institute. Prior to that she was Deputy Director of the Jonsson Comprehensive Cancer Center at UCLA. She evaluates Cancer Center Administration, planning and evaluation processes, developmental and programmatic activities, as well as services provided by Shared Resources during an annual two-day on-site review. Ms. Addis submits a written report to the Director, who shares the report with Associate Directors, Program Leaders, applicable Shared Resource Scientific Directors and Facility Directors/Managers, and with the CCSAB, and implements the recommendations. Ms. Addis has been of invaluable help to the Center Director when defining the structure of the Cancer Center Administration and its seamless integration with the parent institution.
Del E. Webb Neuroscience, Aging and Stem Cell Research Center Scientific Advisory Board
Jonathan Epstein, M.D.
University of Pennsylvania
Rudolph Tanzi, Ph.D.
Massachusetts General Hospital
Torsten Wiesel, M.D.
President Emeritus, Department of Neurobiology
Rockefeller University
Don Price, M.D.
Johns Hopkins University School of Medicine
Gordon Keller, Ph.D.
McEwen Centre for Regenerative Medicine
Eric Olson, Ph.D.
University of Texas at Southwestern
Rudolph Jaenisch, M.D.
Massachusetts Institute of Technology
Cynthia Kenyon, Ph.D.
University of California, San Francisco
Stephen Heinemann, Ph.D.
Salk Institute for Biological Studies
Floyd Bloom, M.D.
The Scripps Research Institute
Diabetes and Obesity Research Center Scientific Advisory Board
Christopher B. Newgard, Ph.D.
Director & Distinguished Professor
W. David & Sarah W. Stedman Nutrition and Metabolism Center,
Duke University Medical Center
Professor, Internal Medicine, Pharmacology, and Cancer Biology
Duke University
Alan D. Attie, Ph.D.
Professor, Department of Biochemistry
University of Wisconsin-Madison
Leslie A. Leinwand, Ph.D.
Professor and Chair, Department of Molecular, Cellular & Developmental Biology
University of Colorado at Boulder
David E. Moller, M.D.
Vice President, Endocrine & Cardiovascular Research & Clinical Investigation
Eli Lilly & Company
David D. Moore, Ph.D.
Professor, Department of Molecular & Cellular Biology
Baylor College of Medicine
Michael D. Schneider, Ph.D.
Professor, Head of Cardiovascular Sciences, and Chair in Cardiology
National Heart and Lung Institute
Imperial College, London
Administrative Leadership
Executive Administrative Leadership
President and
Interim Chief Executive Officer
Professor, NCI-designated Cancer Center
Pauline and Stanley Foster Presidential Chair
(858)646-3100 x3129 kvuori@sanfordburnham.org
Executive Vice President
Chief Administrative Officer, Chief Financial Officer, Treasurer
(858)646-3126 graisl@sanfordburnham.org
Administration
External Relations
Scientific Leadership
Executive Scientific Leadership
President and
Interim Chief Executive Officer
Professor, NCI-Designated Cancer Center
Pauline and Stanley Foster Presidential Chair
Scientific Director, Sanford-Burnham at Lake Nona
Director and Professor, Diabetes and Obesity Research Center
Scientific Director, Sanford-Burnham at La Jolla
Associate Director, NCI-designated Cancer Center
Program Director and Professor, Signal Transduction
Center Directors
Director and Professor, NCI-Designated Cancer Center
Director and Professor, Del E. Webb Neuroscience, Aging and Stem Cell Research Center
Director and Professor, Infectious and Inflammatory Disease Center
Scientific Director, Sanford-Burnham at Lake Nona
Director and Professor, Diabetes and Obesity Research Center
Director and Professor, Sanford Children's Health Research Center
Program Directors
NCI-Designated Cancer Center
Program Director and Professor, Tumor Microenvironment
Director, Academic Affairs
Program Director and Professor, Tumor Development
Scientific Director, Sanford-Burnham at La Jolla
Associate Director, NCI-designated Cancer Center
Program Director and Professor, Signal Transduction
Program Director and Professor, Apoptosis and Cell Death Research
Director, Scientific Education and Training
Del E. Webb Neuroscience, Aging and Stem Cell Research Center
Acting Program Director and Professor, Degenerative Disease Research
Program Director and Professor, Stem Cells and Regenerative Biology
Program Director and Professor, Development and Aging
Infectious and Inflammatory Diseases Center
Program Director and Professor, Infectious Diseases
Program Director and Professor, Inflammatory Diseases
Program Director and Professor, Bioinformatics and Systems Biology
Director, Translational Research for Infectious and Inflammatory Diseases Center
Diabetes and Obesity Research Center
Program Director and Professor, Metabolic Signaling and Disease
Program Director and Professor, Cardiovascular Pathobiology
Sanford Children's Health Research Center
Program Director and Professor, RNA Biology
Program Director and Professor, Genetic Disease
Program Director and Professor, Muscle Development and Regeneration
Shared Resources and Technology Centers
Vice President, Scientific Resources
Cancer Center Associate Director, Shared Resources
Adjunct Associate Professor
Vice President, Drug Discovery and Development
Program Director and Professor, Stem Cells and Regenerative Biology Center Director, Stem Cell Research Center
Center Director and Professor, Translational Research Institute
Talent - Leadership
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